Medical Marijuana For Pets?
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A recent news story about medical marijuana helping a dog for cognitive dysfunction was inaccurate, claiming that THC is very toxic, and that there is no research backing the claims. Dr Jones debiunks the myths. See some of the following links.
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Marijuana poisoning: https://www.ncbi.nlm.nih.gov/pubmed/23796481
Malfait, A., Gallily, R., Sumariwalla, P., Malik, A., Andreakos, E., Mechoulam, R., & Feldmann, M. (2000). The nonpsychoactive cannabis constituent cannabidiol is an oral anti-arthritic therapeutic in murine collagen-induced arthritis. Proceedings of the National Academy of Sciences, 9561-9566.
Costa, B., Colleoni, M., Conti, S., Parolaro, D., Franke, C., Trovato, A., & Giagnoni, G. (2004). Oral anti-inflammatory activity of cannabidiol, a non-psychoactive constituent of cannabis, in acute carrageenan-induced inflammation in the rat paw. Naunyn-Schmiedeberg’s Archives of Pharmacology, 294-299.
Jones, N., Hill, A., Smith, I., Bevan, S., Williams, C., Whalley, B., & Stephens, G. (2009, November 9). Cannabidiol Displays Antiepileptiform and Antiseizure Properties In Vitro and In Vivo. Retrieved December 3, 2015, from http://jpet.aspetjournals.org/content/332/2/569.abstract
Consroe, P., Wolkin, A. (1977).
Cannabidiol–antiepileptic drug comparisons and interactions in experimentally induced seizures in rats. The Journal of Pharmacology and Experimental Therapuetics, 201(1), 26-32.
Jones, N., Glyn, S., Akiyama, S., Hill, T., Hill, A., Weston, S., . . . Williams, C. (n.d.). Cannabidiol exerts anti-convulsant effects in animal models of temporal lobe and partial seizures. Seizure, 344-352.
Malfait, A., Gallily, R., Sumariwalla, P., Malik, A., Andreakos, E., Mechoulam, R., & Feldmann, M. (2000). The nonpsychoactive cannabis constituent cannabidiol is an oral anti-arthritic therapeutic in murine collagen-induced arthritis. Proceedings of the National Academy of Sciences, 9561-9566.
Guimarães, F., Chiaretti, T., Graeff, F., & Zuardi, A. (n.d.). Antianxiety effect of cannabidiol in the elevated plus-maze. Psychopharmacology, 558-559.
Crippa, J., Derenusson, G., Ferrari, T., Wichert-Ana, L., Duran, F.,
Martin-Santos, R., . . . Hallak, J. (2010). Neural basis of anxiolytic effects of cannabidiol (CBD) in generalized social anxiety disorder: A preliminary report. Journal of Psychopharmacology, 121-130.
Integrating cannabis into clinical cancer care: https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4791148/
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